Hybrid cell line for producing monoclonal antibody to a...

Details Hybrid cell line for producing monoclonal antibody to a... Hybrid cell line for producing monoclonal antibody to a...

C - Chemistry, Metallurgy

12

N

195/1.11

C12N 5/02 (2006.01) C12N 15/00 (2006.01)

Patent

CA 1183468

ABSTRACT HYBRID CELL LINE FOR PRODUCING MONOCLONAL ANTIBODY TO A HUMAN T CELL ANTIGEN, ANTIBODY, AND METHODS Hybrid cell line for production of monoclonal antibody to an antigen found on essentially all normal human T cells and on approximately 95% of normal human thymocytes. The hybrid is formed by fusing splenocytes from immunized CAF1 mice with P3X63Ag8Ul myeloma cells. Diagnostic and therapeutic uses of the monoclonal antibody are also disclosed.

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