Hybrid cell lines producing monoclonal antibodies directed...

Details Hybrid cell lines producing monoclonal antibodies directed... Hybrid cell lines producing monoclonal antibodies directed...

C - Chemistry, Metallurgy

12

N

195/1.107

C12N 5/02 (2006.01) A61K 39/02 (2006.01) A61K 39/395 (2006.01) C07K 16/12 (2006.01) C12P 21/00 (2006.01)

Patent

CA 1240938

ABSTRACT Continuous hybrid cell lines for producing monoclonal antibodies directed against antigens of Treponema pallidum have been developed. The hybrid cell lines were estab- lished by fusing differentiated lymphoid cells primed with antigens of Treponema pallidum with hybridoma cells. The resulting fused cells were cloned, isolated, cultured and characterized as to antibody specificity against antigenic determinants of Treponema pallidum.

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