Hybrid genes for gene therapy in erythroid cells

Details Hybrid genes for gene therapy in erythroid cells Hybrid genes for gene therapy in erythroid cells

C - Chemistry, Metallurgy

12

N

C12N 15/85 (2006.01) A61K 31/70 (2006.01) A61K 48/00 (2006.01) C07K 14/805 (2006.01) C12N 15/12 (2006.01)

Patent

CA 2246005

The invention relates to hybrid genes for gene therapy in erythroid cells, and in particular .alpha.-, .beta.-, .delta.-, .epsilon.,.gamma.-, or ~-globin nucleotide sequences operably linked to .beta.-globin regulatory elements. The hybrid genes are useful for treatment of hemoglobinopathies such as sickle cell anemia or .beta.-thalassemia.

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