Hybrid microspheres

Details Hybrid microspheres Hybrid microspheres

B - Operations, Transporting

01

J

167/44, 204/91.5

B01J 13/02 (2006.01)

Patent

CA 1242671

HYBRID MICROSPHERES ABSTRACT Substrates, particularly inert synthetic organic resin heads (10) or sheet (12) such as polystyrene are coated with a covalently bound layer (24) of polyacrolein by irradiation a solution (14) of acrolein or other alde- hyde with high intensity radiation. Individual micro- spheres (22) are formed which attach to the surface to form the aldehyde containing layer (24). The aldehyde groups can be converted to other functional groups by reaction with materials such as hydroxylamine. Adducts of proteins such as antibodies or enzymes can be formed by direct reaction with the surface aldehyde groups.

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