Hybrid monoclonal antibodies and compositions containing them

Details Hybrid monoclonal antibodies and compositions containing them Hybrid monoclonal antibodies and compositions containing them

C - Chemistry, Metallurgy

12

P

C12P 21/08 (2006.01) A61K 47/48 (2006.01) C07K 16/46 (2006.01) C07K 17/02 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2068813

TITLE: HYBRID MONOCLONAL ANTIBODIES AND COMPOSTIONS CONTAINING THEM ABSTRACT The present invention relates to a bispecific antibody having specificity for both a thrombus and a substance having thrombolytic activity, which contains a variable region and lacks heavy chain constant region domains 2 and 3, and a thrombolytic agent comprising said antibody and a thrombolytic substance immunologically bound thereto, whereby its side effects are extremely reduced.

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