Hybrid polypeptides with selectable properties

Details Hybrid polypeptides with selectable properties Hybrid polypeptides with selectable properties

C - Chemistry, Metallurgy

07

K

C07K 19/00 (2006.01) C07K 14/575 (2006.01) C07K 14/585 (2006.01) C07K 14/605 (2006.01)

Patent

CA 2555877

The present invention relates generally to novel, selectable hybrid polypeptides useful as agents for the treatment and prevention of metabolic diseases and disorders which can be alleviated by control plasma glucose levels, insulin levels, and/or insulin secretion, such as diabetes and diabetes-related conditions. Such conditions and disorders include, but are not limited to, hypertension, dyslipidemia, cardiovascular disease, eating disorders, insulin-resistance, obesity, and diabetes mellitus of any kind, including type 1, type 2, and gestational diabetes.

L'invention concerne de nouveaux polypeptides hybrides pouvant être choisis, utiles en tant qu'agents de traitement et de prévention des maladies et des troubles métaboliques pouvant être atténués par la régulation du niveau de glycémie, du niveau d'insuline et/ou de la sécrétion d'insuline, tels que le diabète et les états liés au diabète. Ces maladies et troubles comprennent, entre autres, l'hypertension, la dyslipidémie, les maladies cardio-vasculaires, les troubles alimentaires, la résistance à l'insuline, l'obésité, le diabète sucré de tout type, notamment de type 1 et de type 2, et le diabète gestationnel.

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