Hybrid rna virus

Details Hybrid rna virus Hybrid rna virus

C - Chemistry, Metallurgy

12

N

47/4, 195/1.22,

C12N 15/83 (2006.01) A01H 1/00 (2006.01) A01H 5/00 (2006.01) C07H 21/02 (2006.01) C12N 5/10 (2006.01) C12N 7/00 (2006.01) C12N 7/01 (2006.01) C12N 15/82 (2006.01)

Patent

CA 1337933

A recombinant RNA virus is provided allowing encapsidation of genetically engineered viral sequences in heterologous, preferably rod-shaped coat, protein capsids. Since icosahedral viruses are limited in the amount of RNA they can carry, and rod-shaped viruses are expandable, this invention allows the size of recombinant virus RNA components to be increased (or decreased). Methods of making and using such recombinant viruses are also provided, specifically with respect to the transfection of plants to bring about genotypic and phenotypic changes.

558357

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