Hybridomas and monoclonal antibodies therefrom reactive...

Details Hybridomas and monoclonal antibodies therefrom reactive... Hybridomas and monoclonal antibodies therefrom reactive...

C - Chemistry, Metallurgy

12

P

C12P 21/08 (2006.01) C07K 16/12 (2006.01) C12N 5/18 (2006.01)

Patent

CA 2072741

2072741 9106860 PCTABS00005 A hybridoma cell line produces a monoclonal antibody with reactivity directed specifically to immunodominant antigens from the catfish pathogen Edwardsiella ictaluri, the antigens having molecular weights of about 14,000, 39,000, 48,000, 60,000, 66,000, 83,000, and 93,000 daltons. This antibody is specific for proteins of E. ictaluri but not for other catfish pathogens. It is therefore useful for the positive identification of E. ictaluri from body fluids and tissue of catfish and for identification and purification of the reactive immunodominant antigens.

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