C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 16/30 (2006.01) A61K 39/395 (2006.01) C12N 5/20 (2006.01) C12N 9/88 (2006.01) G01N 33/574 (2006.01) G01N 33/577 (2006.01)
Patent
CA 2374587
Hybridomas secreting monoclonal antibodies specific for an epitope found in the amino acids of LCGA associated with non-small cell lung carcinoma protein have been found. The monoclonal antibodies produced by these hybridomas can be used in in vivo and in vitro clinical diagnosis of non-small cell lung carcinoma and ovarian carcinoma and as target selective carriers for various anti-tumor agents and radioimaging agents.
La présente invention concerne des hybridomes sécrétant des anticorps monoclonaux spécifiques d'un épitope rencontré dans les acides aminés du LCGA associé à la protéine du carcinome du poumon à cellules non-petites. Les anticorps monoclonaux produits par ces hybridomes conviennent particulièrement, d'une part au diagnostic clinique in vivo et in vitro du carcinome du poumon à cellules non petites, ainsi que du carcinome des ovaires, et d'autre part comme vecteurs sélectifs des cibles pour divers antitumoraux et agents de radio-imagerie.
Bollon Arthur P.
Torczynski Richard M.
Bollon Arthur P.
Cytoclonal Pharmaceutics Inc.
Kirby Eades Gale Baker
Torczynski Richard M.
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