Hybridomas producing monoclonal antibodies to new mucin...

Details Hybridomas producing monoclonal antibodies to new mucin... Hybridomas producing monoclonal antibodies to new mucin...

C - Chemistry, Metallurgy

12

N

167/129, 167/139

C12N 5/18 (2006.01) A61K 47/48 (2006.01) A61K 49/00 (2006.01) A61K 51/10 (2006.01) C07K 14/705 (2006.01) C07K 16/30 (2006.01) G01N 33/574 (2006.01) G01N 33/577 (2006.01) A61K 38/00 (2006.01)

Patent

CA 1340815

Novel hybridoma cell lines producing monoclonal antibodies reactive with purified mucin antigens from normal and tumor sources are generated using mucins, including purified mucins from tumor sources. Epitopes on mucin antigens from normal and tumor sources are demonstrated to be distinct, using these new antibodies. The antibodies may be useful alone or in combination, in the diagnosis and treatment of cancer including malignancies of the breast and lung.

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