C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 233/76 (2006.01) A61K 31/4166 (2006.01) A61K 31/4178 (2006.01) C07D 233/78 (2006.01)
Patent
CA 2642794
The present invention relates to compounds of the formula (I), pharmaceutical compositions containing said compounds, methods for the preparation thereof, and methods for their use. The compounds are useful in treating diseases characterized by the hyperactivity of MEK. Accordingly the compounds are useful in the treatment of diseases, such as cancer, cognitive and CNS disorders, and inflammatory/autoimmune diseases.
La présente invention concerne des composés de formule (I), des compositions pharmaceutiques les contenant, leurs méthodes de synthèse et leurs méthodes d'utilisation. Les composés peuvent être employés dans le traitement de maladies caractérisées par l'hyperactivité de la MEK. Ainsi, les composés peuvent être employés dans le traitement de maladies telles que le cancer, les troubles cognitifs et du SNC, ainsi que les maladies inflammatoires/auto-immunes.
Chen Shaoqing
Huby Nicholas John Silvester
Kong Norman
Mischke Steven Gregory
Moliterni John Anthony
F. Hoffmann-La Roche Ag
Gowling Lafleur Henderson Llp
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