Hydantoin derivatives, process for the preparation thereof,...

Details Hydantoin derivatives, process for the preparation thereof,... Hydantoin derivatives, process for the preparation thereof,...

C - Chemistry, Metallurgy

07

D

260/305

C07D 491/107 (2006.01) C07D 493/10 (2006.01) C07D 495/10 (2006.01)

Patent

CA 1167447

ABSTRACT OF THE DISCLOSURE Novel hydantoin derivatives and salts thereof, the process for the preparation thereof, and medicines containing the same, wherein the hydantoin derivatives are represented by the general formula: Image wherein X1 and X2, which may be the same or different, mean independently hydrogen atom, a halogen atom, a lower alkyl group or a lower alkoxy group; Y means oxygen atom or sulfur atom, R1 and R2, which may be the same or different, mean independently hydrogen atom, a lower alkyl group or phenyl group, or the both may form a ring with a carbon atom which is combined with them, excluding the case wherein both R1 and R2 are hydrogen atom at the same time, and n means an interger of 0 or 1. The novel hydantoin derivatives and salts thereof have excellent effects for the treatment of the complications of the diabetes mellitus.

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