Hydantoin derivatives used as mmp inhibitors

Details Hydantoin derivatives used as mmp inhibitors Hydantoin derivatives used as mmp inhibitors

C - Chemistry, Metallurgy

07

D

C07D 403/12 (2006.01) A61K 31/506 (2006.01) A61P 11/00 (2006.01) A61P 11/06 (2006.01) A61P 19/00 (2006.01) A61P 19/02 (2006.01) C07D 239/34 (2006.01)

Patent

CA 2670166

The invention provides compounds of formula (I): wherein R1 and R2are as defined in the specification; processes for their preparation; pharmaceutical compositions containing them; a process for preparing the pharmaceutical compositions; and their use in therapy. The compounds are useful as MMP inhibitors.

L'invention porte sur des composés représentés par la formule (I): dans laquelle R1 et R2 sont tels que définis dans la description; sur des procédés pour leur préparation; sur des compositions pharmaceutiques les contenant; un procédé de fabrication des compositions pharmaceutiques; et sur leur utilisation en thérapie. Les composés sont utiles comme inhibiteurs de MMP.

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