Hydrated crystalline esters of camptothecin for the...

C - Chemistry – Metallurgy – 07 – D

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C07D 491/22 (2006.01) A61K 31/4375 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2703054

Hydrated crystalline camptothecin esters, such as crystalline aliphatic ester hydrates of camptothecin, pharmaceutical compositions containing crystalline aliphatic ester hydrates of camptothecin, methods of treating a cancer or malignant tumor using the crystalline camptothecin ester hydrates and methods of making the same are described.

L'invention concerne des esters de camptothécine cristallins hydratés, tels que des hydrates d'ester aliphatiques cristallins de camptothécine, des compositions pharmaceutiques contenant les hydrates d'ester aliphatique cristallin de camptothécine, des procédés de traitement d'un cancer ou d'une tumeur maligne utilisant les hydrates d'ester de camptothécine cristallin et des procédés de préparation de ces derniers.

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