Hydrates of b-lactam antibiotic

Details Hydrates of b-lactam antibiotic Hydrates of b-lactam antibiotic

C - Chemistry, Metallurgy

07

D

167/231, 260/271

C07D 463/00 (2006.01) A61K 31/44 (2006.01)

Patent

CA 2002596

X-7191 Abstract The crystalline dihydrate and trihydrate forms of the antibiotic 7.beta.-[2'-(R)-2'-phenyl-2'-amino- acetamido]-3-chloro-3-(1-carbadethiacephem)-4-carbboxylic acid ("LY163892") are described. These hydrates are antibiotics in their own right, and are valuable inter- mediates to the corresponding monohydrate form of LY163892.

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