A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 51/08 (2006.01) A61K 49/00 (2006.01) C07K 1/13 (2006.01)
Patent
CA 2613439
The present disclosure is directed to diagnostic agents. More specifically, the disclosure is directed to compounds, diagnostic agents, compositions, and kits for detecting and/or imaging and/or monitoring a pathological disorder associated with coronary plaque, carotid plaque, aortic plaque, plaque of the arterial vessel, aneurism, vasculitis, and other diseases of the arterial wall. In addition, the disclosure is directed to methods of detecting and/or imaging and/or monitoring changes in the arterial wall, including expansive and constrictive remodeling, total vessel wall area, internal lumen size, and exterior artery perimeter.
La présente invention concerne des agents diagnostiques. Plus spécifiquement, cette invention a pour objet des composés, des agents diagnostiques, des compositions et des kits de détection et/ou d'imagerie et/ou de surveillance d'un trouble pathologique associé à une plaque coronaire, une plaque de la carotide, une plaque de l'aorte, une plaque d'artère, un anévrisme, une vascularite et d'autres troubles de la paroi artérielle. En outre, ladite invention a trait à des méthodes de détection et/ou d'imagerie et/ou de surveillance de modifications de la paroi artérielle, y compris, un remodelage expansif et constrictif, une zone de paroi vasculaire entière, une taille de lumière interne et un périmètre d'artère externe.
Cesati Richard R.
Harris Thomas D.
Robinson Simon P.
Yalamanchili Padmaja
Bristol-Myers Squibb Pharma Company
Gowling Lafleur Henderson Llp
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