Hydrochloride salts of 8-[{1-(3,5-bis-(trifluoromethyl)...

Details Hydrochloride salts of 8-[{1-(3,5-bis-(trifluoromethyl)... Hydrochloride salts of 8-[{1-(3,5-bis-(trifluoromethyl)...

C - Chemistry, Metallurgy

07

D

C07D 471/10 (2006.01) A61K 31/438 (2006.01) A61P 1/08 (2006.01)

Patent

CA 2648604

Disclosed are hydrochloride and tosylate crystalline salt forms of (5S,8S)-8- [{(1R)-1 -(3,5-Bis-(trifluoromethyl)phenyl)-ethoxy}-methyl]-8-phenyl-1,7- diazaspiro[4.5]decan-2-one, represented by Formula I and methods of preparing the same.

L'invention concerne des formes cristallines de sels d'hydrochlorure et de tosylate de (5S,8S)-8- [{(1 R)-1-(3,5-Bis-(trifluoromethyl)phenyl)-ethoxy}-methyl]-8-phenyl-1 )7- diazaspiro[4.5]decan-2-one, représentées par la formule (I) et des procédés de préparation desdits sels.

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