Hydrochloride salts of a glycopeptide phosphonate derivative

Details Hydrochloride salts of a glycopeptide phosphonate derivative Hydrochloride salts of a glycopeptide phosphonate derivative

C - Chemistry, Metallurgy

07

K

C07K 9/00 (2006.01) C07H 15/20 (2006.01)

Patent

CA 2543009

Disclosed are hydrochloride salts of telavancin having a chloride ion content of from about 2.4 wt. % to about 4.8 wt. %. The disclosed salts have improved stability during storage at ambient temperatures compared to other hydrochloride salts. Also disclosed are processes for preparing such salts.

L'invention concerne des chlorhydrates de télavancine présentant une teneur en ions chlorure comprise entre environ 2,4 % en poids en environ 4,8 % en poids. Les sels selon l'invention présentent une stabilité améliorée au cours du stockage à des températures ambiantes comparé à d'autres chlorhydrates. L'invention concerne également des procédés de préparation desdits sels.

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