Hydrogel microbeads having a secondary layer

Details Hydrogel microbeads having a secondary layer Hydrogel microbeads having a secondary layer

A - Human Necessities

01

N

A01N 25/28 (2006.01) A61K 8/04 (2006.01) A61K 8/34 (2006.01) A61K 8/35 (2006.01) A61K 8/37 (2006.01) A61K 8/73 (2006.01) A61K 9/50 (2006.01) B01J 13/00 (2006.01) B01J 13/10 (2006.01) B01J 13/14 (2006.01) B01J 13/16 (2006.01)

Patent

CA 2387170

A microbead having a matrix core comprising a hydrophilic matrix and droplets of active material entrained therein, and a secondary layer adjacent to the outer surface of the matrix core. The secondary layer may be ionically complexed or hydrogen bonded to the matrix core surface. Compositions comprising the microbeads suspended in solution may be sprayable. The microbeads of the invention may be controllable by exposing the microbeads to high or low humidity or moisture.

L'invention concerne une microbille possédant un coeur de matrice comportant une matrice hydrophile et des goutellettes de matériau actif entraînées dessus et une couche secondaire adjacente à la surface externe du coeur de matrice. La couche secondaire peut être complexée ioniquement ou liée par hydrogène à la surface du coeur de matrice. Des compositions contenant des microbilles suspendues en solution peuvent se vaporiser. L'invention concerne également des microbilles que l'on peut contrôler en exposant ces dernières à une humidité plus ou moins forte.

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