Hydrogel nanocompsites for ophthalmic applications

Details Hydrogel nanocompsites for ophthalmic applications Hydrogel nanocompsites for ophthalmic applications

A - Human Necessities

61

L

A61L 27/52 (2006.01) A61F 2/16 (2006.01)

Patent

CA 2542512

The present invention relates to reversible hydrogel systems. Particularly, the hydrogel of the present invention is made up of copolymers that can be a hydrogel when in an oxidized state and can be a solution when in a reduced state. A solution of the copolymer can be oxidized to form a hydrogel; and the hydrogel can be reduced to form a solution of the copolymer. Reversible nanogels can also be formed from a dilute solution of the copolymers. The hydrogel is formed with nanoparticles embedded therein to form a nanocomposite whose refractive index and modulus can be controlled by varying the amounts of nanoparticles and the polymer concentration of the hydrogel, respectively

L'invention concerne des systèmes réversibles d'hydrogel. En particulier, ledit hydrogel comporte des copolymères pouvant être un hydrogel sous une forme oxydée et un solution sous une forme réduite. Une solution du copolymère peut être oxydée de façon à former un hydrogel et l'hydrogel peut être réduit de façon à former une solution du copolymère. Des nanogels réversibles peuvent être formés aussi à partir d'une solution diluée des copolymères. L'hydrogel est formé avec des nano-particules noyées dans celui-ci de façon à former un nanocomposite dont l'indice de réfraction et le module peuvent être contrôlés en modifiant les quantités de nano-particules et la concentration de polymère de l'hydrogel respectivement.

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