Hydrogels of polysaccharide mixtures for tissue engineering...

C - Chemistry – Metallurgy – 08 – L

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C08L 5/04 (2006.01) A61K 47/36 (2006.01) A61L 27/52 (2006.01) C08J 3/075 (2006.01) C08L 5/08 (2006.01)

Patent

CA 2652967

The present invention describes the preparation of hydrogels (or 3D matrices) obtainable from aqueous solutions of mixtures of acid polysaccharides and derivatives of basic polysaccharides, such as oligosaccharide derivatives of chitosan. Said solutions are suitably gelled with either chemical or physical gelling agents with the aim of encapsulating either cells, isolated or in multicellular associations, or pharmacologically active molecules, in solution or suspension, for use in the biomedical and pharmaceutical field.

La présente invention concerne la préparation d'hydrogels (ou de matrices 3D) obtenus à partir de solutions aqueuses de mélanges de polysaccharides acides et de dérivés de polysaccharides basiques, par exemple des dérivés d'oligosaccharides du chitosane. Lesdites solutions sont gélifiées de manière appropriée à l'aide d'agents gélifiants chimiques ou physiques dans le but d'encapsuler des cellules, isolées ou associées sous forme multicellulaire, ou des molécules actives sur le plan pharmacologique, en solution ou en suspension, pour des applications dans les domaines biomédical et pharmaceutique.

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