C - Chemistry – Metallurgy – 07 – C
Patent
C - Chemistry, Metallurgy
07
C
C07C 319/02 (2006.01) C07C 309/86 (2006.01) C07C 321/26 (2006.01)
Patent
CA 2399774
This invention relates to a process for the production of an aryl thiol, which comprises hydrogenating an aryl sulfonyl chloride in a solvent in the presence of a palladium catalyst and a base whose conjugate acid has a pKa of about 2 or greater, wherein the base is selected from the group consisting of ionic bases soluble in water and tertiary amines soluble in the solvent, the tertiary amines not having a methyl group attached to the amine nitrogen.
L'invention concerne un procédé de production d'un arylthiol, qui consiste à hydrogéner un chlorure d'arylsulfonyle dans un solvant en présence d'un catalyseur au palladium et d'une base dont l'acide conjugué possède un pK¿a? d'environ 2 ou plus, cette base étant choisie parmi le groupe comprenant des bases ioniques solubles dans l'eau et des amines tertiaires solubles dans le solvant, les amines tertiaires ne contenant pas de groupe méthyle attaché à l'azote de l'amine.
Bennett Jones Llp
E.i. Du Pont de Nemours And Company
The Texas A&m University System
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