C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 339/04 (2006.01) A61K 31/385 (2006.01) A61P 29/00 (2006.01) C07C 327/48 (2006.01) C07C 331/28 (2006.01) C07D 209/28 (2006.01)
Patent
CA 2658433
The present invention relates to derivatives of non-steroidal anti-inflammatory drugs (NSAIDs) having improved anti-inflammatory properties useful in the treatment of inflammation, pain and fever. More particularly, NSAIDs are derivatized with a hydrogen sulfide (H2S) releasing moiety to produce novel anti-inflammatory compounds having reduced side effects.
La présente invention concerne des dérivés d'anti-inflammatoires non stéroïdiens (AINS) présentant de meilleures propriétés anti-inflammatoires utiles pour traiter l'inflammation, la douleur et la fièvre. Plus particulièrement, ces anti-inflammatoires non stéroïdiens (AINS) sont dérivés avec un groupe de libération de sulfure d'hydrogène (H2S) afin qu'on obtienne de nouveaux composés anti-inflammatoires présentant des effets secondaires réduits.
Caliendo Giuseppe
Cirino Giuseppe
Santagada Vincenzo
Wallace John L.
Antibe Therapeutics Inc.
Bennett Jones Llp
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