Hydrogenated rapamycin derivatives

C - Chemistry – Metallurgy – 07 – H

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C07H 19/24 (2006.01) A61K 31/70 (2006.01) C07D 498/18 (2006.01) C07H 19/01 (2006.01)

Patent

CA 2048843

AHP-9666 HYDROGENATED RAPAMYCIN DERIVATIVES Abstract of the Disclosure A derivative of rapamycin where one, two, or three of the double bonds at the 1-, 3-, or 5-positions of rapamycin have been reduced to the corresponding alkane, or a pharmaceutically acceptable salt thereof, which by virtue of its antifungal activity is useful in treating fungal infections. Image RAPAMYCIN

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