C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 495/04 (2006.01) A61K 31/4365 (2006.01) A61P 7/02 (2006.01)
Patent
CA 2722248
The present invention relates to crystalline form I of Prasugrel hydrogensulfate. A process for the preparation of these salts, pharmaceutical compositions comprising the salts and the use of the salts as a pharmaceutical, in particular as a blood platelet aggregation inhibitor are also described. Seed crystals which can be employed in the above mentioned process as well as a process for their preparation are also disclosed.
La présente invention porte sur une forme cristalline I de l'hydrogénosulfate de Prasugrel. L'invention porte également sur un procédé pour la fabrication de ces sels, sur des compositions pharmaceutiques comprenant les sels et sur l'utilisation des sels comme produit pharmaceutique en particulier comme inhibiteur de l'agrégation plaquettaire. L'invention porte également sur des germes cristallins qui peuvent être employés dans le procédé mentionné ci-dessus ainsi que sur un procédé pour leur fabrication.
Hotter Andreas
Pichler Arthur
Wieser Josef
Goudreau Gage Dubuc
Sandoz Ag
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