Hydrolysis process

C - Chemistry – Metallurgy – 12 – P

Patent

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167/308, 195/128

C12P 21/06 (2006.01) A61K 8/65 (2006.01) A61K 8/98 (2006.01)

Patent

CA 1108542

ABSTRACT OF THE DISCLOSURE The invention relates to a process for the preparation of water-soluble hydrolysates from keratin-containing materials (such as hair and wool), which process comprises subjecting a keratin-containing material to an acidic treatment at a pH not exceeding 2 and at a temperature of at least 80°C whereby partial hydrolysis of the said material is effected, and subsequently subjecting the resulting product to enzymatic hydrolysis in the presence of urea with an alkaline protease having an optimum enzymatic activity in the pH range of 9 to 13, the enzymatic hydrolysis being effected at least initially at a pH at which the said alkaline protease has optimum enzymatic activity whereby a water-soluble hydrolysate is produced. The process of the invention may be used to produce keratin-hydrolysates of optimum molecular weight and amino acid content (for example for use in therapeutic cosmetic preparations).

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