Hydrolytically degradable hydrophilic gels and the method...

C - Chemistry – Metallurgy – 08 – J

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C08J 3/24 (2006.01) A61K 9/20 (2006.01) A61K 47/32 (2006.01) C07C 239/22 (2006.01) C07C 259/06 (2006.01) C08F 220/36 (2006.01) C08F 220/58 (2006.01) C08K 5/32 (2006.01)

Patent

CA 2032581

Hydrolytically degradable hydrophilic gels and the method for preparation thereof The solution pertains to hydrolytically degradable hydro- philic gels consisting of the individual chains of hydrophilic polymer interconnected with crosslinks containing the structure unit Image The method for preparation of the hydrolytically degrad- able gels consists in subjecting hydrophilic monomers or their mixture to the radical polymerization or copolymerization, or to copolymerization with hydrophobic monomers, in the pre- sence of a new compound - N,O-dimethacryloylhydroxylamine - as a crosslinking agent, and, if desired, in the presence of a solvent, whereas the amount of hydrophilic monomers is 50 to 99.8 molar percent related to all monomers present.

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