Hydrophilic article and method of producing same

B - Operations – Transporting – 01 – D

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18/1184, 18/32

B01D 71/42 (2006.01) B01D 67/00 (2006.01) B01J 20/32 (2006.01)

Patent

CA 1302677

HYDROPHILIC ARTICLE AND METHOD OF PRODUCING SAME Abstract of the Disclosure This invention provides a matrix comprising molecules of a nitrile-containing polymer which provides solely on the surface of the matrix sufficient uncharged sub- stituted amides groups to render the surface hydrophilic. The invention also provides an article of manufacture comprising the matrix. Another aspect of the invention provides a method of producing a matrix having a hydrophilic surface which comprises treating molecules of a nitrile-containing polymer so as to derivatize a portion of the nitrile groups of the polymer and provide solely on the surface of the matrix sufficient uncharged, hydrophilic substi- tuted amide groups to render the surface hydrophilic. Another embodiment of the invention concerns improved methods of filtration, ultrafiltration, microfiltra- tion, reverse osmosis, dialysis, pervaporation, siev- ing, affinity chromatography, affinity purification, affinity separation, or affinity adsorption which com- prises using the article of manufacture.

557537

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