Hydrophilic binary systems for the administration of...

A - Human Necessities – 61 – K

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A61K 38/13 (2006.01) A61K 9/107 (2006.01) A61K 47/00 (2006.01) A61K 47/10 (2006.01) A61K 47/14 (2006.01) A61K 47/26 (2006.01) A61K 47/32 (2006.01) A61K 47/44 (2006.01) A61K 9/48 (2006.01)

Patent

CA 2284000

Binary pharmaceutical compositions comprising (i) a cyclosporine compound, (ii) a hydrophilic phase and (iii) a surfactant, provide bioavailability of the active ingredient which is equivalent to that provided by ternary compositions, but without the need for a lipophilic phase.

L'invention concerne des compositions pharmaceutiques binaires comprenant (i) un composé de cyclosporine, (ii) une phase hydrophile et (iii) un tensioactif; les compostions selon l'invention permettent d'obtenir une biodisponibilité de l'ingrédient actif équivalente à celle produite par des compositions ternaires, mais sans nécessité d'une phase lipophile.

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