Hydrophilic biocompatible adhesive formulations and uses

Details Hydrophilic biocompatible adhesive formulations and uses Hydrophilic biocompatible adhesive formulations and uses

A - Human Necessities

61

K

A61K 50/00 (2006.01) A61K 47/32 (2006.01) A61L 15/58 (2006.01) A61K 9/70 (2006.01)

Patent

CA 2596529

This invention relates to the use of hydrophilic, biocompatible adhesives in drug delivery systems, wound dressings, bioelectrodes, and other systems in which hydrophilic, biocompatible adhesives are desirable. In particular, the invention relates to water-swellable, water-insoluble polymers that in combination render a composition adhesive upon contact with moisture, wherein a first water-swellable, water-insoluble polymer is cationic, a second water- swellable, water-insoluble polymer is anionic, and the polymers are ionically associated with each other to form a polymer matrix.

La présente invention concerne l'utilisation d'adhésifs hydrophiles biocompatibles dans des systèmes d'administration de médicaments, des pansements pour lésions, des bioélectrodes ainsi que d'autres systèmes dans lesquels les adhésifs hydrophiles biocompatibles présentent un avantage. L'invention concerne notamment des polymères hydrodilatables insolubles dans l'eau qui, en association, rendent une composition adhésive lors d'un contact avec de l'humidité, un premier polymère hydrodilatable non soluble dans l'eau est cationique, un second polymère hydrodilatable non soluble dans l'eau est anionique et les polymères sont associés ioniquement l'un à l'autre pour former une matrice polymère.

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