Hydrophilic coating for an intracorporeal medical device

Details Hydrophilic coating for an intracorporeal medical device Hydrophilic coating for an intracorporeal medical device

A - Human Necessities

61

L

A61L 29/00 (2006.01) A61L 29/04 (2006.01) A61L 29/08 (2006.01) A61L 31/00 (2006.01) A61L 31/04 (2006.01) A61L 31/10 (2006.01)

Patent

CA 2316223

It has been discovered that compositions which are blends or mixtures including a monomeric fatty acid component can serve as stable lubricity additives in distillate fuels, including gasoline. The compositions may include saturated or unsaturated, monomeric fatty acids having from 12 to 22 carbon atoms; a synthetic monomeric acid having from 12 to 40 carbon atoms; and saturated or unsaturated, oligomeric fatty acids having from 24 to 66 carbon atoms. Where a saturated monomeric fatty acid is used, a hindered and/or tertiary amine may be present as a stabilizer.

L'invention concerne un procédé de fourniture d'un revêtement thérapeutique, diagnostique ou hydrophile lubrifiant sur un dispositif médical intracorporel et le dispositif pourvu du revêtement ainsi obtenu, ledit revêtement étant durable. Selon un mode de réalisation, le revêtement comprend une couche de base polymérisée et une couche supérieure thérapeutique, diagnostique ou hydrophile, la couche de base étant pourvue d'un composant de liaison qui relie la couche supérieure, un composant de greffage qui lie le composant de liaison et adhère au dispositif. Selon un autre mode de réalisation, le revêtement comprend un mélange d'un composé hydrophile, d'un composant de greffage et d'un sel, le composant de greffage polymérisé comprenant des domaines non réticulés. Le revêtement de l'invention peut être appliqué sur un dispositif médical pourvu d'une surface polymère telle qu'un cathéter polymère ou un dispositif métallique recouvert ou non d'un primaire polymère ou sur un stent.

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