Hydrophilic diagnostic devices for use in the assaying of...

G - Physics – 01 – N

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G01N 33/48 (2006.01)

Patent

CA 2444836

Diagnostic in-vitro devices for use in the assaying of biological fluids are provided which include cover plates or backing strips which exhibit hydrophilic properties to assist in transport of the biological fluid or retention of same within the device. Exemplary diagnostic devices include lateral flow devices, microfluidic devices and microtiter plates. The devices may also be comprised of low fluorescent material in order to facilitate any diagnostic determination by use of fluorescent emissions. Hydrophilic properties may be imparted to the cover plates or backing strips by physical or chemical treatment thereof. The cover plates or backing strips may exhibit heat sealable or pressure sensitive properties.

L'invention concerne des dispositifs diagnostiques in vitro destinés à être utilisés pour analyser des fluides biologiques. Ces dispositifs comprennent des plaques de recouvrement ou des bandes de soutien qui présentent des propriétés hydrophiles pour favoriser le transport du fluide biologique ou sa rétention dans le dispositif. Ces dispositifs diagnostiques peuvent être des dispositifs à écoulement latéral, des dispositifs microfluidiques ou des plaques de microtitrage. Les dispositifs peuvent en outre être composés d'une matière à faible fluorescence afin de faciliter toute détermination diagnostique au moyen d'émissions fluorescentes. Les propriétés hydrophiles peuvent être conférées aux plaques de recouvrement ou aux bandes de soutien par traitement physique ou chimique. Les plaques de recouvrement ou les bandes de soutien peuvent présenter des propriétés de thermoscellage ou de sensibilité à la pression.

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