Hydrophilic light absorbing compositions for determination...

Details Hydrophilic light absorbing compositions for determination... Hydrophilic light absorbing compositions for determination...

A - Human Necessities

61

K

A61K 49/00 (2006.01) A01N 43/38 (2006.01) C07D 209/08 (2006.01) C07D 209/12 (2006.01) C07D 209/56 (2006.01) C07D 209/58 (2006.01) C07D 209/60 (2006.01)

Patent

CA 2425698

Highly hydrophilic indole and benzoindole derivatives that absorb and fluoresce in the visible region of light are disclosed. These compounds are useful for physiological and organ function monitoring. Particularly, the molecules of the invention are useful for optical diagnosis of renal and cardiac diseases and for estimation of blood volume in vivo.

L'invention concerne des dérivés de benzoindole et d'indole fortement hydrophiles qui absorbent la lumière et sont fluorescents dans le spectre visible de la lumière. Ces composés sont utiles dans le contrôle des fonctions physiologique et organique. Plus précisément, les molécules selon l'invention sont utiles dans le diagnostic optique de maladies cardiaques et rénales, et dans l'estimation de la volémie in vivo.

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