Hydrophilic microparticles and methods to prepare same

Details Hydrophilic microparticles and methods to prepare same Hydrophilic microparticles and methods to prepare same

A - Human Necessities

61

K

A61K 9/10 (2006.01) A61K 31/4164 (2006.01) A61K 31/4545 (2006.01) A61K 31/498 (2006.01) B01J 13/10 (2006.01)

Patent

CA 2555678

(57) The present invention comprises a material and a method of its preparation. The material may be described as hydrophilic microparticles, comprising a cluster of organic substance with a layer of polyelectrolyte on its surface. The present invention establishes an improved method for preparing aqueous colloidal dispersions of water-insoluble organic substances using polyionic hydrophilic polymers by which the stability of the suspension is maintained after removal of the stabilizing and/or solubilizing medium of the drug. This improved method can be utilized to formulate a variety of water- insoluble organic substances.

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