Hydrophilic polymer blends used for dry cow therapy

A - Human Necessities – 61 – K

Patent

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Details

A61K 47/34 (2006.01) A61K 9/08 (2006.01) A61K 31/047 (2006.01) A61K 31/085 (2006.01) A61K 31/155 (2006.01) A61K 33/18 (2006.01) A61K 47/32 (2006.01) A61P 17/00 (2006.01) A61P 31/02 (2006.01)

Patent

CA 2427520

The present invention provides a mammalian teat dip composition capable of being used during a mammal's dry period comprising a solution of a film- forming polymer blend comprising a first polymer component which is an organic, solvent-soluble, preformed, thermoplastic polyurethane having no reactive isocyanate groups and a second polymer component which is a hydrophilic poly(N-vinyl lactam), said blend capable of withstanding exposure to water without significant loss of said hydrophilic poly(N-vinyl lactam) in an amount sufficient to form a water-resistant film upon topical application to mammalian skin; and wherein said blend comprises from about 10 to about 80 weight percent of said first polymer in combination with said solvent and from about 1 to about 20 weight percent of said second polymer; and at least one antimicrobial agent in an amount sufficient to treat and protect mammalian skin from infection; wherein said composition is capable of being removed by peeling.

La présente invention concerne une composition de trempage des trayons d'un mammifère pouvant être utilisée au cours de la période sèche d'un mammifère, comprenant une solution composée d'un mélange de polymères feuillogène comprenant un premier composant polymérique constitué d'un polyuréthane thermoplastique organique, soluble dans un solvant et préformé, ne comprenant pas de groupes d'isocyanate réactifs, et un second composant polymérique constitué d'un poly(N-vinyl lactame) hydrophile, ledit mélange pouvant résister à l'exposition à l'eau sans perte significative dudit poly(N-vinyl lactame) hydrophile en une quantité suffisante pour former un film résistant à l'eau après application topique sur la peau du mammifère. Ledit mélange comprend également d'environ 10 à environ 80 pour cent en poids dudit premier polymère en combinaison avec ledit solvant et d'environ 1 à environ 20 pour cent en poids dudit second polymère; et au moins un agent antimicrobien en une quantité suffisante pour traiter et protéger la peau du mammifère des infections. Ladite composition peut être éliminée par pelage.

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