Hydrophilic polyurethane compositions

C - Chemistry – Metallurgy – 08 – G

Patent

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Details

C08G 18/32 (2006.01) A61K 9/00 (2006.01) C08G 18/48 (2006.01) C08G 18/66 (2006.01)

Patent

CA 2656489

A water-swellable linear polymer is made by reacting together a polyethylene oxide of number average molecule weight less than 4000, an aliphatic diol and a difunctional isocyanate. Controlled release composition comprises the polymer together with an active agent. The polymer is able to take up pharmaceutically active agents of molecular weight 200 to 20,000.

Polymère linéaire gonflant à l'eau réalisé en faisant réagir un oxyde de polyéthylène ayant une masse moléculaire moyenne en nombre inférieure à 4000, avec un diol aliphatique et un isocyanate difonctionnel. Une composition à libération contrôlée comprend le polymère avec un agent actif. Le polymère est capable de prélever des agents pharmaceutiquement actifs ayant une masse moléculaire comprise entre 200 et 20 000.

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