Hydrophobic core carrier compositions for delivery of...

A - Human Necessities – 61 – K

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Details

A61K 47/30 (2006.01) A61K 47/32 (2006.01) A61K 51/06 (2006.01) A61P 3/10 (2006.01)

Patent

CA 2633070

The present invention relates, in part, to a biocompatible hydrophobic-core carrier comprising a carrier, and a plurality of hydrophobic groups covalently linked to the polymeric carrier. The hydrophobic groups are capable of dissociably linking load molecules such as therapeutic agents. The hydrophobic- core carrier may also comprise protective side chains, orienting molecules, and targeting molecules.

La présente invention concerne en partie un support biocompatible à noyau hydrophobe, comprenant un support et une pluralité de groupes hydrophobes liés de manière covalente au support polymère. Les groupes hydrophobes sont capables de lier de manière dissociable des molécules telles que des agents thérapeutiques. Le support à noyau hydrophobe peut également comprendre des chaînes latérales protectrices, des molécules d'orientation et des molécules de ciblage.

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