Hydrophobic crosslinked copolymer and a method for producing...

C - Chemistry – Metallurgy – 08 – F

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402/125, 402/507

C08F 218/00 (2006.01) B01J 20/26 (2006.01) C08F 220/12 (2006.01) C08F 246/00 (2006.01) G01N 30/48 (1990.01)

Patent

CA 1334119

A hydrophobic crosslinked copolymer having a pendant group selected from Image , Image and Image , wherein R1 represents at least one hydrophobic group having a hydrophobic fragmental constant of at least 1.5, which copolymer has a high crosslinking monomer units content, a specific surface area and a specific acetonitrile regain value. The hydrophobic crosslinked copolymer has a high rigidity as well as an excellent mechanical strength and an excellent chemical stability so that the copolymer is use- ful as a packing for liquid chromatography, particularly reversed phase partition chromatography. This hydrophobic crosslinked copolymer can be advantageously produced by a method in which a crosslinked copolymer having a side chain of small length is first produced, and then a substitution reaction to introduce a hydrophobic group of large length is effected with respect to the side chain of small length.

549895

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