Hydrophobic preparations

A - Human Necessities – 61 – K

Patent

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Details

A61K 9/107 (2006.01) A23L 1/035 (2006.01) A61K 8/14 (2006.01) A61K 8/64 (2006.01) A61K 8/66 (2006.01) A61K 38/17 (2006.01) B01J 13/00 (2006.01) C07K 1/14 (2006.01) C12N 9/00 (2006.01)

Patent

CA 2176577

Single phase preparations of hydrophilic species, in particular macromolecular compounds such as proteins or glycoproteins in a hydrophobic solvent such as an oil can be obtained by preparing a hydrophile/amphiphile array in which the hydrophilic head groups of the amphiphile are orientated towards the hydrophilic species and bringing the array into contact with the hydrophobic solvent. The preparations of the invention can be used alone or can be combined with an aqueous phase to form emulsions in which the hydrophilic species is present in the hydrophobic phase. The compositions of the present invention are versatile and have application in the pharmaceutical, food, cosmetic, chemical and agricultural industries.

Des préparations à phase unique d'espèces hydrophiles, en particulier des composés macromoléculaires, tels que des protéines ou des glycoprotéines dans un solvant hydrophobe, tel qu'une huile, peuvent s'obtenir par la préparation d'une combinaison hydrophile/amphiphile dans laquelle les groupes principaux hydrophiles de l'amphiphile sont orientés vers l'espèce hydrophile, ainsi que par la mise en contact de ladite combinaison avec le solvant hydrophobe. Ces préparations peuvent s'utiliser seules ou être combinées à une phase aqueuse, de façon à obtenir des émulsions dans lesquelles l'espèce hydrophile est présente dans la phase hydrophobe. Ces compositions sont polyvalentes et peuvent s'utiliser dans les industries pharmaceutique, alimentaire, cosmétique, chimique et agricole.

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