A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 47/14 (2006.01) A61K 9/107 (2006.01) A61K 9/127 (2006.01) A61K 38/23 (2006.01) A61K 38/28 (2006.01) A61K 45/08 (2006.01) A61K 47/28 (2006.01)
Patent
CA 2259233
Hydrophobic preparations which are useful as, among other things, pharmaceutical delivery systems comprise: (i) an oil phase comprising one or more medium chain monoglycerides, such as Akoline MCMTM; (ii) at least one amphiphile, preferably including a phospholipid such as phosphatidyl choline; and (iii) a hydrophilic species, which may be a protein such as insulin or calcitonin or another macromolecule, solubilised or otherwise dispersed in the one or more glycerides. (The hydrophilic species is one that is not normally soluble in the glycerides).
Préparations hydrophobes utiles, entre autres, en tant que systèmes d'administration pharmaceutique et comprenant: (i) une phase huileuse contenant un ou plusieurs monoglycérides de chaîne moyenne, tels qu'Akoline MCM?TM¿; (ii) au moins un amphiphile, de préférence, contenant un phospholipide, tel que phosphatidylcholine; (iii) une espèce hydrophile qui peut être une protéine, telle qu'insuline ou calcitonine ou une autre macromolécule, solubilisée ou sinon dispersée dans le ou les glycérides. (L'espèce hydrophile est une espèce qui n'est pas soluble normalement dans les glycérides).
Kirby Christopher John
New Roger Randal Charles
Cortecs (uk) Limited
Sim & Mcburney
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