Hydrophobically enhanced aminoglycosides

Details Hydrophobically enhanced aminoglycosides Hydrophobically enhanced aminoglycosides

C - Chemistry, Metallurgy

07

H

C07H 13/12 (2006.01) A61K 31/702 (2006.01) A61K 31/7028 (2006.01) A61K 31/7036 (2006.01) A61K 47/48 (2006.01) A61P 31/04 (2006.01) C07H 15/12 (2006.01)

Patent

CA 2729852

Hydrophobically enhanced aminoglycosides have been prepared and shown to be effective antibacterial agents. These agents may be used in the treatment or prevention of various bacterial infections. Methods of preparing these agents also permit facile synthetic access Formula (I).

L'invention concerne des aminoglycosides améliorés au plan de l'hydrophobicité, qui ont été préparés et se sont révélés des agents antibactériens efficaces. Ces agents peuvent être utilisés dans le traitement ou la prévention de diverses infections bactériennes. Des procédés de préparation de ces agents permettent également leur accès facile par synthèse.

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