C - Chemistry – Metallurgy – 07 – C
Patent
C - Chemistry, Metallurgy
07
C
C07C 259/06 (2006.01) A61K 31/16 (2006.01) A61K 31/195 (2006.01) A61K 31/395 (2006.01) A61K 31/66 (2006.01) C07C 237/22 (2006.01) C07C 311/46 (2006.01) C07C 317/26 (2006.01) C07C 323/41 (2006.01) C07D 209/48 (2006.01) C07D 213/56 (2006.01) C07D 295/13 (2006.01) C07F 9/30 (2006.01)
Patent
CA 2184093
This disclosure relates to a novel class of hydroxamic and carboxylic acid based matrix metalloproteinase inhibitor derivatives. The disclosure further relates to pharmaceutical compositions containing such compounds and to the use of such compounds and compositions in the treatment of matrix metalloproteinase induced diseases.
La présente invention concerne une nouvelle classe de dérivés de l'acide hydroxamique et de l'acide carboxylique, ayant pour propriété d'inhiber la métalloprotéinase matricielle. Elle porte, en outre, sur des compositions pharmaceutiques contenant ces composés et sur l'utilisation de ces composés et de ces compositions dans le traitement de maladies induites par la métalloprotéinase matricielle.
Cook Ewell R.
Gowravaram Madhusudhan Reddy
Johnson Jeffrey
Mathiowetz Alan M.
Saha Ashis K.
Fetherstonhaugh & Co.
Sanofi-Synthelabo
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