Hydroxamic acid derivatives and method of using same

C - Chemistry – Metallurgy – 07 – C

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167/269, 260/549

C07C 259/08 (2006.01) A61K 31/16 (2006.01) A61K 31/185 (2006.01)

Patent

CA 1292244

ABSTRACT HYDROXAMIC ACID DERIVATIVES AND METHOD USING SAME In accordance with the present invention, new hydroxamic acid derivatives useful as .DELTA.5-lipoxygenase inhibitors are provided. These new compounds have the general formula Image wherein Image and Image are cycloalkyl groups which may be the same or different; R is hydrogen, lower alkyl, aryl, lower alkenyl, cycloalkyl or aralkyl; n is an integer from 3 to 12; and m is an integer from 3 to 12. Further in accordance with the present invention, a method for using the above compounds is provided.

541013

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