Hydroxamic acid derivatives useful as antibacterial agents

Details Hydroxamic acid derivatives useful as antibacterial agents Hydroxamic acid derivatives useful as antibacterial agents

C - Chemistry, Metallurgy

07

C

C07C 239/14 (2006.01) A61K 31/16 (2006.01)

Patent

CA 2735929

The invention relates to a compound of formula (I): or a pharmaceutically acceptable salt thereof, thereof, wherein: G is a group of formula (II); and pharmaceutically acceptable salts, prodrugs, hydrates, or solvates, thereof, wherein A, B. L1-L4 A, B, R1-R4 and m are as defined herein. The invention also relates to pharmaceutical compositions comprising the compounds of formula (I) and their use in treating a bacterial infection.

L'invention concerne un composé de formule (I) : ou l'un de ses sels pharmaceutiquement acceptables, formule dans laquelle : G représente un groupe de formule (II), et ses sels, promédicaments, hydrates ou solvats pharmaceutiquement acceptables, où A, B. L1-L4 A, B, R1-R4 et m sont tels qu'il est défini ici. L'invention concerne également des compositions pharmaceutiques comprenant les composés de formule (I) et leur utilisation dans le traitement d'une infection bactérienne.

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