C - Chemistry – Metallurgy – 07 – H
Patent
C - Chemistry, Metallurgy
07
H
260/210, 260/228
C07H 19/01 (2006.01) C07H 23/00 (2006.01)
Patent
CA 1316916
6940P/5357A 10/10/88:Fl 17831 TITLE OF THE INVENTION NOVEL HYDROXIDE MEDIATED FK-506 REARRANGEMENT PRODUCT ABSTRACT OF THE INVENTION A process is described involving an alkaline rearrangement of FK-506 producing a new decarbonylated 22-membered macrocycle rearrangement derivative of FK-506, i.e. C.9, nor-keto FK-506.
615340
Askin David
Jones Todd K.
Reamer Robert A.
Shinkai Ichiro
Volante Ralph P.
Askin David
Gowling Lafleur Henderson Llp
Jones Todd K.
Merck & Co. Inc.
Reamer Robert A.
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