Hydroxy alkyl amides of dicarboxylic acids and their use in...

C - Chemistry – Metallurgy – 07 – C

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C07C 233/18 (2006.01) A61K 8/68 (2006.01) A61Q 19/00 (2006.01)

Patent

CA 2144452

A class of pseudoceramide having the formula shown in which: R1 is a hydrocarbon group; R2-R8 are each independently H or CH3; R9 and R10 are each independently H or hydrocarbon group of up to 24 C atoms; X1 and X2, are independently H or OH; Y1 and Y2 are H or OH, at least one of Y1 and Y2 being OH; wherein the C atom Z, with associated R9 and R10, can be absent; and the C atoms W, with associated R7 and Y2, can be absent, is disclosed. These find use in compositions, particularly cosmetic compositions, suitable for topical application to skin, hair or nails.

L'invention concerne une classe de pseudocéramides ayant la formule (II) dans laquelle R1 représente un groupe hydrocarbure; R2-R8 représentent indépendamment H ou CH3; R9 et R10 représentent chacun indépendamment H ou un groupe hydrocarbure possédant jusqu'à 24 atomes de carbone; X1 et X2 représentent indépendamment H ou OH; Y1 et Y2 représentent H ou OH, Y1 et/ou Y2 représentant OH. L'atome de carbone Z, et R9 et R10 associés, peuvent être absents; et les atomes de carbone W, et R7 et Y2 associés, peuvent être absents. Ces pseudocéramides peuvent être utilisés dans des compositions, notamment des compositions cosmétiques, conçues pour s'appliquer localement sur la peau, les cheveux ou les ongles.

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