Hydroxy alkyl amine derivatives as beta-secretase inhibitors...

C - Chemistry – Metallurgy – 07 – C

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C07C 317/26 (2006.01) A61K 31/165 (2006.01) A61K 31/325 (2006.01) A61K 31/33 (2006.01) C07C 271/18 (2006.01) C07C 317/46 (2006.01) C07C 317/48 (2006.01) C07C 317/50 (2006.01) C07C 323/39 (2006.01) C07C 323/60 (2006.01) C07C 327/32 (2006.01) C07D 207/12 (2006.01) C07D 207/26 (2006.01) C07D 207/28 (2006.01) C07D 209/08 (2006.01) C07D 211/16 (2006.01) C07D 211/46 (2006.01) C07D 211/96 (2006.01) C07D 213/30 (2006.01) C07D 213/81 (2006.01) C07D 213/82 (2006.01) C07D 231/14 (2006.01) C07D 233/54 (2006.01) C07D 23

Patent

CA 2448834

Disclosed are compounds of formula X, where Rn, R20, R1, R2, R3, and Rc are defined herein. These compounds are useful in treating Alzheimer's disease and other similar diseases. Pharmaceutical compositions comprising compounds of formula X and methods of preparing the compounds of formula X are also disclosed.

La présente invention concerne des composés de formule X, dans laquelle R¿n?, R¿20?, R¿1?, R¿2?, R¿3?, et R¿c? sont définis. Lesdits composés sont utiles dans le traitement de la maladie d'Alzheimer et d'autres maladies similaires. L'invention concerne également des compositions pharmaceutiques comprenant des composés de formule X et des procédés de préparation desdits composés de formule X.

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