Hydroxy diphenyl urea sulfonamides as il-8 receptor antagonists

A - Human Necessities – 61 – K

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A61K 31/17 (2006.01) A61K 31/40 (2006.01) A61K 31/445 (2006.01) A61K 31/535 (2006.01) A61K 31/54 (2006.01) C07C 273/00 (2006.01) C07C 275/00 (2006.01) C07C 311/47 (2006.01) C07C 317/28 (2006.01) C07C 323/49 (2006.01) C07D 205/04 (2006.01) C07D 207/10 (2006.01) C07D 207/22 (2006.01) C07D 207/34 (2006.01) C07D 207/48 (2006.01) C07D 211/28 (2006.01) C07D 211/80 (2006.01) C07D 213/76 (2006.01) C07D 215/16 (2006.01) C07D 215/20 (2006.01) C07D 215/36 (2006.01) C07D 241/04 (2006.01) C07D 261/02 (2006.01) C07D 265/

Patent

CA 2355890

The invention relates to novel hydroxy diphenylurea sulfonamides, compositions and intermediates thereof. The hydroxy diphenylurea sulfonamides are useful in the treatment of disease states mediated by the chemokine, Interleukin-8.

La présente invention concerne de nouveaux sulfonamides hydroxydiphénylurée, des compositions et des intermédiaires de ceux-ci. Les sulfonamides hydroxydiphénylurée sont utiles dans le traitement d'états pathologiques dont la médiation est assurée par la chimiokine interleukine 8.

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