Hydroxy substituted 1h-imidazopyridines and methods

Details Hydroxy substituted 1h-imidazopyridines and methods Hydroxy substituted 1h-imidazopyridines and methods

C - Chemistry, Metallurgy

07

D

C07D 471/04 (2006.01) A61K 31/437 (2006.01) A61P 37/02 (2006.01)

Patent

CA 2620933

Hydroxy substituted 1H-imidazo[4,5-c]pyridin-4-amines, with a hydroxy substituent at the 2-position, pharmaceutical compositions containing these compounds, methods of making the compounds, intermediates, and methods of use of these compounds as immunomodulators, for inducing cytokine biosynthesis in animals and in the treatment of diseases including viral and neoplastic diseases, are disclosed.

La présente invention propose des 1H-imidazo[4,5-c]pyridin-4-amines substituées par un hydroxy, avec un substituant hydroxy à la position 2, des compositions pharmaceutiques contenant ces composés, des procédés de préparation des composés, des intermédiaires, et des procédés d'utilisation de ces composés en tant qu'immunomodulateurs, pour induire la biosynthèse de cytokine chez des animaux et dans le traitement de maladies comprenant des maladies virales et néoplasiques.

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