Hydroxy-substituted cephalosporins

Details Hydroxy-substituted cephalosporins Hydroxy-substituted cephalosporins

C - Chemistry, Metallurgy

07

D

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C07D 501/24 (2006.01) A61K 31/545 (2006.01) C07D 205/08 (2006.01) C07D 213/89 (2006.01) C07D 233/84 (2006.01) C07D 239/38 (2006.01) C07D 249/02 (2006.01) C07D 257/04 (2006.01) C07D 271/10 (2006.01) C07D 279/06 (2006.01) C07D 285/12 (2006.01) C07D 501/06 (2006.01) C07D 501/20 (2006.01) C07D 501/32 (2006.01) C07D 501/36 (2006.01) C07D 501/44 (2006.01) C07D 501/60 (2006.01)

Patent

CA 1065853

A B S T R A C T New cephalosporin antibiotics are provided. The compounds have the general formula Image (I) , wherein R is a hydrogen atom, an esterified carboxy or carboxy group, and Y is a lower alkanoyl, lower alkoxy or azido or a group of the formula -SR3 in which R3 is a heteroxyclic residue. They are prepared by acylation of a suitable 7-aminocephalosporanic acid derivative.

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